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Vectors for Mouse Kmt2a

Gene Information

  • Offical Gene Symbol Kmt2a
  • Species Mouse (Mus musculus)
  • Offical Full Name lysine (K)-specific methyltransferase 2A
  • Other Aliases 6430520K01; ALL-1; All1; Cxxc7; HRX; HTRX1; Mll; Mll1; mKIAA4050
  • Other Desigations histone-lysine N-methyltransferase 2A; cysteine methyltransferase KMT2A; histone-lysine N-methyltransferase MLL; myeloid/lymphoid or mixed-lineage leukemia protein 1; trithorax Drosophila; zinc finger protein HRX
  • Gene Type protein-coding
  • Summary
    Enables DNA binding activity; chromatin binding activity; and histone methyltransferase activity (H3-K4 specific). Involved in several processes, including definitive hemopoiesis; regulation of gene expression; and regulation of histone modification. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; macromolecule methylation; and regulation of histone modification. Located in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; hematopoietic system; nervous system; and retina. Used to study acute lymphoblastic leukemia and acute myeloid leukemia. Human ortholog(s) of this gene implicated in acute myeloid leukemia; cervical cancer; mixed phenotype acute leukemia; and non-Hodgkin lymphoma. Orthologous to human KMT2A (lysine methyltransferase 2A). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 214162
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Kmt2a(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kmt2a expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Kmt2a expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Kmt2a expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Kmt2a expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Kmt2a expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kmt2a shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Kmt2a shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Kmt2a shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Kmt2a shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Kmt2a CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
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Mouse Kmt2a CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Kmt2a CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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