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Vectors for Mouse Pitx2

Gene Information

  • Offical Gene Symbol Pitx2
  • Species Mouse (Mus musculus)
  • Offical Full Name paired-like homeodomain transcription factor 2
  • Other Aliases 9430085M16Rik; Brx1; Brx1b; Munc30; Otlx2; Ptx2; Rieg
  • Other Desigations pituitary homeobox 2; ALL1-responsive protein ARP1; BRX1 homeoprotein; orthodenticle-like homeobox 2; paired-like homeodomain transcription factor Munc 30; solurshin
  • Gene Type protein-coding
  • Summary
    Enables DNA-binding transcription factor activity, RNA polymerase II-specific; chromatin DNA binding activity; and sequence-specific DNA binding activity. Involved in animal organ development and left/right axis specification. Acts upstream of or within several processes, including animal organ development; circulatory system development; and embryonic hindlimb morphogenesis. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and musculature. Used to study Axenfeld-Rieger syndrome type 1 and glaucoma. Human ortholog(s) of this gene implicated in Arts syndrome; Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 1; anterior segment dysgenesis 4; and ring dermoid of cornea. Orthologous to human PITX2 (paired like homeodomain 2). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 18741
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Pitx2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pitx2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Pitx2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Pitx2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Pitx2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Pitx2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pitx2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Pitx2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Pitx2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Pitx2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pitx2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Pitx2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Pitx2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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