Vectors for Mouse Pvt1

Gene Information

Offical Gene Symbol Pvt1
Species Mouse (Mus musculus)
Offical Full Name Pvt1 oncogene
Other Aliases Ayu21-84Imeg; Gt(pU21)84Imeg; Mis-1; Mlvi-1; Pvt-1
Other Desigations plasmacytoma variant translocation 1
Gene Type ncRNA
Summary
This gene produces a long non-coding RNA that has been identified as a candidate oncogene. In humans, increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Consistently, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. In mouse, this gene has also been found to be a potential regulator of cardiac hypertrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
NCBI Gene ID 19296
RefSeq Transcript
NM_011222.1
RefSeq Protein
-
External Links NCBI | Ensembl | UCSC Genome Browser View
View ORF sequence of this gene »

No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

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