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Vectors for Rat Pml

Gene Information

  • Offical Gene Symbol Pml
  • Species Rat (Rattus norvegicus)
  • Offical Full Name PML nuclear body scaffold
  • Other Aliases RGD1562602
  • Other Desigations protein PML; promyelocytic leukemia
  • Gene Type protein-coding
  • Summary
    Predicted to enable several functions, including protein dimerization activity; transition metal ion binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including regulation of cellular protein metabolic process; regulation of nucleobase-containing compound metabolic process; and signal transduction by p53 class mediator. Predicted to act upstream of or within several processes, including apoptotic signaling pathway; positive regulation of macromolecule metabolic process; and protein localization to nucleus. Predicted to be located in chromosome, telomeric region; cytosol; and nucleus. Predicted to be extrinsic component of endoplasmic reticulum membrane. Predicted to be active in PML body and chromatin. Predicted to colocalize with heterochromatin. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia and skin cancer. Orthologous to human PML (PML nuclear body scaffold). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 315713
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Rat Pml(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pml expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Rat Pml expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Rat Pml expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Rat Pml expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Rat Pml expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pml shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Rat Pml shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Rat Pml shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Rat Pml shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pml CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Rat Pml CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Rat Pml CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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