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Vectors for Rat Pten

Gene Information

  • Offical Gene Symbol Pten
  • Species Rat (Rattus norvegicus)
  • Offical Full Name phosphatase and tensin homolog
  • Other Aliases MMAC1; Mmac; TEP1
  • Other Desigations phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; inositol polyphosphate 3-phosphatase; mutated in multiple advanced cancers 1; phosphatase and tensin homolog deleted on chromosome ten; protein tyrosine phosphatase and tensin-like protein
  • Gene Type protein-coding
  • Summary
    Enables several functions, including PDZ domain binding activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to hormone stimulus; dephosphorylation; and negative regulation of transport. Located in several cellular components, including dendritic spine; mitochondrion; and postsynaptic membrane. Is active in postsynaptic cytosol. Used to study portal hypertension and substance-related disorder. Biomarker of several diseases, including acute myocardial infarction; fatty liver disease; glucose metabolism disease (multiple); retinal disease (multiple); and transient cerebral ischemia. Human ortholog(s) of this gene implicated in several diseases, including PTEN hamartoma tumor syndrome (multiple); breast cancer (multiple); gastrointestinal system cancer (multiple); nervous system cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human PTEN (phosphatase and tensin homolog). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 50557
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Rat Pten(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pten expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Rat Pten expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Rat Pten expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Rat Pten expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Rat Pten expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pten shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Rat Pten shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Rat Pten shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Rat Pten shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Pten CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Rat Pten CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Rat Pten CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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