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Vectors for Zebrafish nrxn1a

Gene Information

  • Offical Gene Symbol nrxn1a
  • Species Zebrafish (Danio rerio)
  • Offical Full Name neurexin 1a
  • Other Aliases -
  • Other Desigations neurexin 1a; neurexin Ia-alpha; neurexin Ia-beta; neurexin-1a-alpha
  • Gene Type protein-coding
  • Summary
    This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. In zebrafish, morpholino knockdown of an alpha isoform results in defects in balance and reduced locomotor activity. Knockdown of a beta isoform results in defects in sprouting angiogenesis and vascular remodeling. Alternative splicing and promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2016]
  • NCBI Gene ID 565531
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Zebrafish nrxn1a(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Zebrafish nrxn1a expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Zebrafish nrxn1a expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Zebrafish nrxn1a expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Zebrafish nrxn1a expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Zebrafish nrxn1a expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189

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