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Vectors for Human PIM1

Gene Information

  • Offical Gene Symbol PIM1
  • Species Human (Homo sapiens)
  • Offical Full Name Pim-1 proto-oncogene, serine/threonine kinase
  • Other Aliases PIM
  • Other Desigations serine/threonine-protein kinase pim-1; Oncogene PIM1; pim-1 oncogene (proviral integration site 1); proto-oncogene serine/threonine-protein kinase pim-1
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • NCBI Gene ID 5292
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PIM1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PIM1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PIM1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PIM1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PIM1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PIM1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PIM1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PIM1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PIM1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PIM1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PIM1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PIM1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PIM1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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