Mouse Bmp8b (Gene ID: 12164) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol Bmp8b
Species Mouse (Mus musculus)
Offical Full Name bone morphogenetic protein 8b
Other Aliases Op3
Other Desigations bone morphogenetic protein 8B
Gene Type protein-coding
Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein may play a role in the generation of primordial germ cells, and has been shown to stimulate thermogenesis in brown adipose tissue. Male mice lacking a functional copy of this gene exhibit variable degrees of germ-cell deficiency. Homozygous knockout mice of both sexes exhibit impaired thermogenesis and reduced metabolic rate, resulting in weight gain. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 4. [provided by RefSeq, Jul 2016]
NCBI Gene ID 12164
RefSeq Transcript
NM_007559.5
RefSeq Protein
NP_031585.2
External Links NCBI | Ensembl | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Mouse Bmp8b expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Mouse Bmp8b expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Mouse Bmp8b expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Mouse Bmp8b expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Mouse Bmp8b expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Mouse Bmp8b shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Mouse Bmp8b shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Mouse Bmp8b shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Mouse Bmp8b shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Mouse Bmp8b CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Mouse Bmp8b CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Mouse Bmp8b CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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