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Vectors for Mouse Flna

Gene Information

  • Offical Gene Symbol Flna
  • Species Mouse (Mus musculus)
  • Offical Full Name filamin, alpha
  • Other Aliases ABP-280; Dilp2; F730004A14Rik; Fln1; GENA 379; filamin-1
  • Other Desigations filamin-A; actin-binding protein 280; dilated pupils 2; endothelial actin-binding protein; non-muscle filamin
  • Gene Type protein-coding
  • Summary
    Enables potassium channel regulator activity and protein kinase C binding activity. Involved in several processes, including circulatory system development; regulation of ion transmembrane transport; and regulation of neuron projection development. Acts upstream of or within actin cytoskeleton organization; early endosome to late endosome transport; and epithelial to mesenchymal transition. Located in several cellular components, including Z disc; axonal growth cone; and trans-Golgi network. Is expressed in several structures, including bone; brain; great vessel of heart; gut; and heart. Used to study periventricular nodular heterotopia. Human ortholog(s) of this gene implicated in X-linked recessive disease (multiple); bone development disease (multiple); heart valve disease (multiple); periventricular nodular heterotopia; and terminal osseous dysplasia. Orthologous to human FLNA (filamin A). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 192176
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Flna(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Flna expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Flna expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Flna expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Flna expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Flna expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Flna shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Flna shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Flna shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Flna shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Flna CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Flna CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Flna CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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