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Vectors for Mouse Notch4

Gene Information

  • Offical Gene Symbol Notch4
  • Species Mouse (Mus musculus)
  • Offical Full Name notch 4
  • Other Aliases Int-3; Int3; N4
  • Other Desigations neurogenic locus notch homolog protein 4; Notch gene homolog 4
  • Gene Type protein-coding
  • Summary
    Enables Notch binding activity. Involved in branching involved in blood vessel morphogenesis and negative regulation of endothelial cell differentiation. Acts upstream of or within several processes, including negative regulation of Notch signaling pathway; positive regulation of angiogenesis; and positive regulation of aorta morphogenesis. Located in cytoplasmic vesicle and endoplasmic reticulum. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system gland. Used to study arteriovenous malformations of the brain. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); dementia; ductal carcinoma in situ; schizophrenia; and systemic scleroderma. Orthologous to human NOTCH4 (notch receptor 4). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 18132
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Notch4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Notch4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Notch4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Notch4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Notch4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Notch4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Notch4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Notch4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Mouse Notch4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Mouse Notch4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Notch4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Notch4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Notch4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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