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Vectors for Mouse Pnkp

Gene Information

  • Offical Gene Symbol Pnkp
  • Species Mouse (Mus musculus)
  • Offical Full Name polynucleotide kinase 3'- phosphatase
  • Other Aliases 1810009G08Rik; PNK
  • Other Desigations bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase
  • Gene Type protein-coding
  • Summary
    Enables ubiquitin ligase-substrate adaptor activity. Involved in cellular response to DNA damage stimulus and protein K63-linked ubiquitination. Part of SCF ubiquitin ligase complex. Is active in site of double-strand break. Is expressed in cerebellum; cerebral cortex; liver; and spleen. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B2 and microcephaly, seizures, and developmental delay. Orthologous to human PNKP (polynucleotide kinase 3\'-phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 59047
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Pnkp(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pnkp expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Pnkp expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Pnkp expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Pnkp expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Pnkp expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pnkp shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Pnkp shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Pnkp shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Pnkp shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Pnkp CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Pnkp CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Pnkp CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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