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Vectors for Mouse Prkdc

Gene Information

  • Offical Gene Symbol Prkdc
  • Species Mouse (Mus musculus)
  • Offical Full Name protein kinase, DNA activated, catalytic polypeptide
  • Other Aliases DNA-PKcs; DNAPDcs; DNAPK; DNPK1; DOXNPH; HYRC1; XRCC7; dxnph; p460; scid; slip
  • Other Desigations DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; doxorubicin nephropathy; severe combined immunodeficiency
  • Gene Type protein-coding
  • Summary
    Enables DNA-dependent protein kinase activity; double-stranded DNA binding activity; and enzyme binding activity. Involved in several processes, including regulation of cellular protein metabolic process; regulation of hematopoietic stem cell differentiation; and regulation of hemopoiesis. Acts upstream of or within several processes, including DNA metabolic process; ectopic germ cell programmed cell death; and immune system development. Located in nucleus. Is expressed in several structures, including central nervous system; neural retina; and thymus primordium. Used to study severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Human ortholog(s) of this gene implicated in immunodeficiency 26. Orthologous to human PRKDC (protein kinase, DNA-activated, catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 19090
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Prkdc(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkdc expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Prkdc expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Prkdc expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Prkdc expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Prkdc expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkdc shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Prkdc shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Prkdc shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Prkdc shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkdc CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Prkdc CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Prkdc CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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