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Vectors for Mouse Prkn

Gene Information

  • Offical Gene Symbol Prkn
  • Species Mouse (Mus musculus)
  • Offical Full Name parkin RBR E3 ubiquitin protein ligase
  • Other Aliases Park2
  • Other Desigations E3 ubiquitin-protein ligase parkin; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkin protein
  • Gene Type protein-coding
  • Summary
    Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway; positive regulation of cellular protein metabolic process; and positive regulation of dendrite extension. Acts upstream of or within several processes, including catecholamine metabolic process; chemical synaptic transmission; and mitophagy. Located in mitochondrion; neuron projection; and nucleus. Part of protein-containing complex. Is expressed in several structures, including face; nervous system; pancreas; sensory organ; and skeleton. Used to study Parkinson\'s disease 2. Human ortholog(s) of this gene implicated in Parkinson\'s disease; Parkinson\'s disease 2; and ovarian cancer. Orthologous to human PRKN (parkin RBR E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 50873
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Prkn(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkn expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Prkn expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Prkn expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Prkn expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Prkn expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkn shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Prkn shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Prkn shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Prkn shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Prkn CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Prkn CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Prkn CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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