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Vectors for Rat Nrxn1

Gene Information

  • Offical Gene Symbol Nrxn1
  • Species Rat (Rattus norvegicus)
  • Offical Full Name neurexin 1
  • Other Aliases Nrxn1b
  • Other Desigations neurexin-1; 60S ribosomal protein L10a pseudogene; neurexin I-alpha; neurexin I-beta; neurexin-1-alpha; neurexin-1-beta; non-processed neurexin I-alpha
  • Gene Type protein-coding
  • Summary
    This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. [provided by RefSeq, Nov 2016] Annotation information: Note: There is an assembly problem in the Rnor_6.0 reference genome assembly, and therefore, annotation of this gene is split across NW_007905831.1, NW_007905830.1, and NW_007905829.1 in NCBI\'s Rattus norvegicus Annotation Release 105. [17 Jun 2015]
  • NCBI Gene ID 60391
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Nrxn1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Nrxn1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Nrxn1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Nrxn1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Nrxn1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Nrxn1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Nrxn1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Rat Nrxn1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Rat Nrxn1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Rat Nrxn1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Nrxn1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
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Rat Nrxn1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Rat Nrxn1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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