Vectors for Western clawed frog txnrd3

Gene Information

  • Offical Gene Symbol txnrd3
  • Species Western clawed frog (Xenopus tropicalis)
  • Offical Full Name thioredoxin reductase 3
  • Other Aliases -
  • Other Desigations thioredoxin reductase 3
  • Summary
    The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals and some vertebrates. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes the third TrxR, which unlike the other two isozymes, contains an additional N-terminal glutaredoxin (Grx) domain, and shows highest expression in testis. The Grx domain allows this isozyme to participate in both Trx and glutathione systems. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 779989
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI

Popular Vector Designs for Western clawed frog txnrd3(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Western clawed frog txnrd3 expression regular plasmid vector Mammalian Gene Expression Vector EGFP/Puro From $159
Western clawed frog txnrd3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector EGFP:T2A:Puro From $159
Western clawed frog txnrd3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector EGFP From $159
Western clawed frog txnrd3 expression AAV vector Mammalian Gene Expression AAV Vector EGFP From $159
Western clawed frog txnrd3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector EGFP/Puro From $159

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