Vectors for Mouse Gdnf

Gene Information

  • Offical Gene Symbol Gdnf
  • Species Mouse (Mus musculus)
  • Offical Full Name glial cell line derived neurotrophic factor
  • Other Aliases ATF
  • Other Desigations glial cell line-derived neurotrophic factor; astrocyte-derived trophic factor; neurotrophic factor
  • Gene Type protein-coding
  • Summary
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Homozygous knockout mice for this gene exhibit defects in kidney development and neonatal death. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
  • NCBI Gene ID 14573
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Gdnf(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdnf expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Mouse Gdnf expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Mouse Gdnf expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Mouse Gdnf expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Mouse Gdnf expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdnf shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
View Vector 
Mouse Gdnf shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
View Vector 
Mouse Gdnf shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
View Vector 
Mouse Gdnf shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdnf CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
View Vector 
Mouse Gdnf CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
View Vector 
Mouse Gdnf CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
View Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

Design My Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Send Design Request

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including:

  • Virus packaging
  • CRISPR targeting
  • BAC modification
  • Library construction
  • Plasmid DNA Preparation
  • RNA preparation
  • Mutagenesis
  • and more...