Click to refer colleagues and get 30% off

HiExpress™ Firefly Luciferase IVT saRNA

VectorBuilder’s HiExpressTM Firefly Luciferase IVT saRNA contains self-amplifying sequences and has been codon optimized for robust and prolonged gene expression. This saRNA contains Cap1, validated 5’ and 3’ UTRs, and has a 110 nt polyA tail.

Ordering Information Price Match

Click here to view the amino acid sequence translated from HiExpressTM Firefly Luciferase IVT saRNA >>

Shipping and storage

Our IVT saRNA products are stored in a 1 mM sodium citrate buffer (pH 6.4) and can be stored at -80°C for up to 12 months. The products are shipped on dry ice and should be avoided for freeze-thaw cycles.

Experimental Validation

 saRNA exhibited extended expression in vivo compared to conventional mRNA.

Figure 1. saRNA exhibited extended expression in vivo compared to conventional mRNA. The expression of 30 µg firefly luciferase mRNA encapsulated in LNP was no longer detected 48 h after intramuscular injection in mice. The expression of the 10 µg saRNA counterpart, however, was detected up to 8 days after injection.

Resources