Testimonials

VectorBuilder is proud to share our client's testimonials:

  • VectorBuilder has been instrumental in supporting my research by providing timely and reliable vector cloning and virus packaging services. Joaquin is always responsive to my requests and vector design needs, efficiently addressing them with care and attention to detail. His dedication to the success of my projects has contributed to several publications. I highly recommend their services.

    Dr. Bogang Wu

    Harvard Medical School, USA

  • In our recent publication titled “Dietary ω3 Fatty Acids Inhibit Tumorigenesis in a MYCN-Driven Neuroblastoma Mouse Model” (Cancers 2024, 17, 362), we utilized the MYCN ORF expression vector custom-built by VectorBuilder, which played a vital role in driving the success of our study.

    Our lab frequently orders from VectorBuilder, and their service has always been outstanding. The team is highly responsive and collaborative and consistently delivers high-quality constructs and glycerol stocks with quick turnaround. They work hand-in-hand with us throughout the design and ordering process, ensuring precision and performance.

    The MYCN ORF vector was central to our project on MYCN-driven neuroblastoma, and it performed robustly in both in vitro and in vivo models. VectorBuilder’s products and support remain valuable assets in our molecular biology research.

    I highly recommend VectorBuilder to other scientists looking for dependable, custom-built vector solutions.

    Dr. Vishwaben Mukeshbhai Patel

    University of Texas at Austin, USA

  • The products were of high quality and we were able to use these to knockdown genes in vivo, and to understand roles of orphan/understudied proteins in vivo. The team was very responsive and professional.

    Dr. Haopeng Xiao

    Stanford University, USA

  • VectorBuilder is the best platform for designing and synthesizing constructs. The online vector design tool is so convenient and fun to use. Ms. Joyce Zhang is always very professional in replying my questions and does it so timely. One time, something did not work out, the refund process was smooth and all the staff were very nice and professional. The constructs I asked for had two fluorescent proteins with two promotors, one has NLS and the other does not. I did transfection and it worked out very well. Joyce helped me all through this process, making my life very easy. Basically, I had many pleasant experiences with Vectorbuilder, and I strongly recommend using it. I had tried other companies, they turned out to be either slow or lacked strong technical support or are expensive. Vectorbuilder is not the cheapest, but considering the quality of its service, it is worth the money.

    Dr. Shanshan Zhu

    Johns Hopkins University, USA

  • We’ve been using VectorBuilder’s services for plasmid construction as well as AAV and lentiviral vector production for several years. Their high-quality products and reliable technical support have greatly accelerated our research and made working with them an excellent experience.

    Dr. Farnaz Shamsi

    New York University, USA

  • It has been a great experience working with VB. I was one of the first to test their empty capsid (AAV VLP) service. For my batch capsids were nearly completely empty (>97% by AUC and TEM) and were thus a huge help for assay development as a negative control. I also want to highlight that my contact Matthew Wheeler was always very helpful and transparent for any queries I had and that the team is very agile. A big plus is also the very intuitive website. Overall, a big thumbs up for VectorBuilder from my side.

    Dr. Andrei Hutanu

    Roche, Switzerland

  • We've used VectorBuilder for three different lentiviral shRNA plasmids, and each one worked exactly as expected with reliable knockdown efficiency. The process was smooth from design to delivery, and their customer support was responsive and helpful throughout. Highly recommend them for high-quality custom vectors.

    Dr. Sonja Arneaud

    University of Texas Southwestern Medical Center, USA

  • Vector Builder’s user-friendly vector design tool, quick turn-around times, and reliable products allow us to drive research forward with confidence. Aside from their products, the team at Vector Builder is readily available to answer questions, provide updates, and offer discounts where possible!

    Mary Zlotosch

    Monte Rosa Therapeutics, USA

  • Two years ago, when another CRO was struggling to provide the requested clones that I ordered, I reached out to Vector Builder to try to make them for me. Very difficult clones to make due to many repeats of amino acids. They got the clones done for me with no issues and very quickly. I have been using Vector Builder since then. Along with this, working with Alejandro Izurieta (California Territory Manager) has been great. He is knowledgeable, and professional promptly answers my request and is courteous. I rely on him to get the service that I need from Vector Builder done. He is just wonderful!

    Irena Levin

    Takeda, USA

  • Our research challenge

    Our work involves primary brain cells, including neurons, human astrocytes, and endothelial cells. These cells are notoriously challenging to maintain and to transduce with viruses for gene overexpression or downregulation.

    How VectorBuilder helped to solve this challenge

    VectorBuilder provided a wide range of lentiviral constructs for gene overexpression and downregulation, which allowed us to specifically target genes in primary brain cells. The viral vectors and particles are highly efficient, easy to handle, and facilitated our research significantly.

    Our experience with VectorBuilder

    We are extremely satisfied with the service provided by VectorBuilder. All of the vectors and viruses have performed reliably, and customer support has been excellent—always responsive and helpful with troubleshooting. Having used VectorBuilder’s services for over five years, we are very pleased with the quality and consistency of your service and would greatly appreciate any incentives or discounts on future purchases.

    Dr. Tsvetkov lab

    The University of Texas Health Science Center at Houston, USA

  • VectorBuilder is my favorite company! The service is reliable, efficient and excellent. The website user interface is intuitive. The number of choices for different vectors and downstream services is exhaustive, and the prices are reasonable. Furthermore, the team is receptive to feedback and queries. Compared to the old days of cloning, VectorBuilder now saves us enormous time and money, and frees us up to focus on the experimental questions rather than getting bogged down with making constructs.

    Dr. Timothy Cripe

    Nationwide Children’s Hospital, USA

  • We are testing different vectors for T cell therapy, and VectorBuilder provides a one stop solution for design, construct and manufacturing numerus lentiviral vectors for us. One of our vector was GMP manufactured by VectorBuilder and move to FDA approved clinical trial. We had great experience working with VectorBuilder, from communication to product QC, high level of service.

    Xueqing Xia

    UT MD Anderson Cancer Center, USA

  • I have been a frequent vectorbuilder customer for the last three years. Their vectors and lentivirus preps have always been reliable and high titer, and I have had a lot of experimental success using their products. Above all else, their customer service is excellent. They are very responsive and have assisted me innumerable times with vector design and other questions, offered me discounts, etc. Vectorbuilder has been instrumental to my experimental success in the lab.

    Dr. Charles Danan

    Children's Hospital of Philadelphia, USA

  • VectorBuilder has greatly assisted our research, facilitating hypothesis testing through intramuscular injections of recombinant adeno-associated viral serotype 6 (rAAV6):Slirp vectors. The support from their team ensured that the vector met our needs, and their production methods delivered reliable results. We appreciate their valuable contribution to our research.

    Dr. Tang Cam Phung Pham

    University of Copenhagen, Denmark

  • We were working on nascent DNA processing at stalled replication forks in BRCA-deficient cells and used a lentiviral construct and CRISPR/Cas9-mediated genome editing from VectorBuilder to create our knockout cell lines. The VectorBuilder support team have great technical expertise, are very supportive and fantastic to work with. I highly recommend VectorBuilder's services to accelerate research projects.

    Dr. George-Lucian Moldovan

    The Pennsylvania State University, USA

  • I have been using Vector Builder to purchase vectors designed to express shRNA. I have found the technical support very helpful and friendly. They will make suggestions that will improve the vectors I design. Customer support is also quite fast in their responses to my questions and have also been quite accomodating with some of my requests. They also provide very helpful diagrams of their vectors that make it easy for anyone to visualize. I highly recommend Vector Builder.

    Dr. Victor Ruiz-Velasco

    Penn State College of Medicine

  • Before using VectorBuilder, producing lentiviral overexpression vectors for our in vitro models was a recurring and time-consuming enterprise. We faced frequent challenges in every experimental step, which made it difficult to plan the actual experiments. Setting up the process with VectorBuilder was very efficient, thanks to their great expertise and support. Once we started using VectorBuilder's services, we noticed a substantial increase in productivity as well as a more uniform and predictable transduction pattern of our target cells.

    We went on to use VectorBuilder for a large-scale CRISPR screen with a custom library spanning over 1,600 genes. With the provided virus, we were able to easily maintain cell representation and we derived a number of interesting hit genes, which we are excited to follow up on. A big thank you to the entire VectorBuilder Team!

    Dr. Dominic Schmid

    University of Basel

  • I am very satisfied with the constructions (double mutants) made by Vectorbuilder. The service is very serious and rigorous. They started by verifying our plasmid by doing digestions. As this was not enough, they even sequenced part of the plasmid, which then ensured the success of the constructs. Constant email exchanges for verification steps were ensured with almost instantaneous responsiveness! Quite impressive! Once the sequence was clarified, production was not long, and we were able to do our experiments under excellent conditions. The results were as good as we expected. Bravo again and thank you for the efficiency, the rigor, and the seriousness.

    Sabine Levi

    French National Centre for Scientific Research (CNRS), France

  • Our lab has been using VectorBuilder to aid in the design and synthesis of plasmids for the last 3-4 years. They have always been extremely helpful with design requests. I would highly recommend VectorBuilder's services to anyone wanting to accelerate their research progress.

    Dr. Andrew Cox

    Peter MacCallum Cancer Centre, Australia

  • We routinely turn to VectorBuilder for the design and production of vectors used to overexpress or silence genes in our translational research on multiple myeloma. Their team has been consistently helpful in addressing technical hurdles related to gene delivery and expression in our models.

    Working with VectorBuilder has always been a smooth experience — communication is clear, timelines are reliable, and the quality of the vectors has been key to the success of several experiments. They’ve become a trusted partner in our work.

    Dr. Debora Soncini

    University of Genoa, Italy

  • Using VectorBuilder has transformed the way I do my research. VectorBuilder’s easy-to-use web interface allows me to custom build my own plasmids, freeing up time that I would have wasted cloning and instead letting me focus on the research that really matters. They offer great prices with a fast turnaround time. Their friendly and well-informed technical support team are on hand every step of the way, should you need any help. I would strongly recommend VectorBuilder to anyone wanting to accelerate the progress of their research.

    Dr. David M Brown

    University of Nottingham, UK

  • VectorBuilder's service is simply amazing. Even if you only have an idea of what you want to do, the VectorBuilder experts will help you make it happen. The service is straightforward and really accommodating. This includes fast delivery and quick responses to queries. I recommend the service to all my colleagues and will definitely use them again for future projects.

    Dr. Stephan Kuenzel

    TU Dresden, Germany

  • Working with VectorBuilder has been a fantastic experience for our lab's vector design and AAV packaging needs. Their expertise and efficiency in handling our project were invaluable, especially given our complex requirements. The team was incredibly responsive and thorough, and Joseph Perez, in particular, was outstanding in guiding us through every step and addressing all of our questions. Thanks to their support, we received high-quality vectors in a timely manner, which has allowed us to move forward smoothly with our research.

    Dr. Yutong Shang

    Case Western Reserve University, USA

  • Amazing experience cooperating with VectorBuilder! As one of the most popular technologies, mRNA vaccine technology has been used extensively to develop therapeutics and vaccines targeting various infectious and non-infectious diseases. Recently, Daniel Meng’s R&D team at VectorBuilder rapidly established the IVT mRNA CRO platform, and we closely collaborated on developing mRNA-based HIV and influenza vaccines. I am so impressed by their scientific vision as well as their problem solving capabilities. Once again, VectorBuilder is trustworthy.

    Dr. Caijun Sun

    Sun Yat-sen University, China

  • I have been using VectorBuilder's cloning service for several years and am extremely happy with their products and services. Their online design software is very easy to use and provides the most cutting edge solutions for today's most demanding molecular cloning needs. Their customer service is outstanding, with great technical competence and the delivery of my vectors was on time. I have saved months of precious research time by using VectorBuilder. I would recommend VectorBuilder to anyone who wants the best vector design and molecular cloning services.

    Dr. Guohao Dai

    Northeastern University, USA

  • One year, over 10 constructs and transgenic fly lines further within a year, I want to thank VB and especially Joseph Perez for their excellent service. Dedicated to getting us the vectors we need, and advancing our follow-up applications- thank you for helping us advance our work!

    Jelly Soffers

    University of Missouri - Kansas City, USA

  • VectorBuilder’s online vector design platform is user friendly and easy to use. All one needs to do is select sequences of inserts either from their vast data base or provide one’s own unique sequences. The sequence database provides a wealth of information and links to peer-reviewed publications. Placing order for the vectors is easy and their technical and supporting staff are prompt in offering solutions. They offer services at low prices in comparison to other commercial sources. With the guaranteed service, I can concentrate on my experiments instead of constructing the vector. Thanks are especially due to Stella Gideon for her support at every step. If one is constrained with time and manpower to devote to vector construction, leave it to VectorBuilder. It is worth every penny.

    Bala Kolli

    Wayne State University, USA

  • I have been working with VectorBuilders since 2017 and generated a knock-in Long Evans rat model that recapitulates neuronal and skin disorders found in humans. In addition, we have designed and generate several plasmid constructs with them. In the past year, Ricky Nemeth, PhD, our Territory Manager, has been very supportive and fantastic to work with. In all, the entire team of VB are great to work with as they are responsive to queries and provide us good quality vectors, viral constructs and viral particles.

    Martin-Paul Agbaga

    University of Oklahoma Health Sciences Center, USA

  • Quality, fast and easy. I must say that VectorBuilder is the best. Very good support during all the order process as well, from the design to the shipment.

    Vitor Oliveira

    Universidade Federal de São Paulo, Brazil

  • Dr. Jen Kong and Jessi Toumeh have been absolutely wonderful to work with on my project to design a very involved viral targeting strategy. I have changed multiple aspects of the vectors and asked them so many questions. Each time they have happily altered the designs, answered my questions, or dug into the literature to find the answers. It has been such a pleasure to work with them. I am so grateful for their patience and expertise. I greatly look forward to future projects with them!

    Dr. Lovisa LjungQvist Brinson

    University of Pittsburgh, USA

  • I had a great experience with Vectorbuilder. Their vector design interface is very user-friendly and intuitive. The products I ordered arrived in a timely manner—within about two weeks—and I received excellent support while troubleshooting one of my experiments. Additionally, their team responded quickly to my inquiries, ensuring a smooth experience overall.

    Dr. Ana Dias

    University of Ottawa, USA

  • VectorBuilder was an amazing resource during my PhD and served me months, if not years, of time that I would otherwise have spent cloning. The support team was great, and the construct was of extremely high quality!

    Dr. Maggie Fye

    Vanderbilt University, USA

  • VectorBuilder has been a great resource for both custom-designed and pre-made AAVs. Their team is always quick to respond, making discussions easy and helping to find the best solutions for our experiments. The support has been excellent, making the entire process smooth and efficient.

    Dr. Evgeniya Shmeleva

    Tufts University, USA

  • I ordered the Myocardin overexpression eGFP tagged plasmid for Co-IP and it works great. But even moreso, the customer support I received from Dr. Joseph Perez was remarkable. He helped me with questions regarding my experimental design and when I needed to order more purified plasmid over the winter break, he made sure it was delivered to the lab upon my return so I could get back to experiments immediately. I would highly recommend Vector Builders just because of the amazing customer service provided by Joseph. I appreciate you so much Dr. Joseph Perez, thanks for all of your support and excellent delivery of services! Vector Builder, please give him a raise, he deserves one!!!!

    Dr. Skylar King

    University of Missouri School of Medicine, USA

  • We utilized two lentiviral vectors, lenti-CYP and lenti-Ctr, from VectorBuilder Inc. in our study on Lgr5+ intestinal stem cells. The lenti-CYP vector, encoding the hCYP27B1 gene, enabled de novo synthesis of locally high 1,25(OH)2D concentrations, proving crucial for our investigation. The high-quality design, including promoter specificity and integrated resistance genes, ensured reliable gene expression and successful transduction. The control vector, lenti-Ctr, further allowed precise experimental comparisons. VectorBuilder's products significantly contributed to the success of our research, and I highly recommend their custom vector services for advanced molecular biology applications.

    Dr. Shaikh Nisar Ali

    Long Island University, USA

  • I have used the Vectorbuilder Lentivirus to do transduction many times. The quality is reliable and the transduction efficiency is very high. The customer service and R&D teams are highly professional and helpful. My experience with VectorBuilder is great.

    Yichuan Wang

    Frederick National Laboratory, USA

  • I had a great experience with the service and Maria solved all our doubts.

    Julian Bergier

    Stamm Bio, Argentina

  • Reliable, precise, and fast, we were well-assisted and supported on purchases, agreements, and technical aspects. For many years we have been working with Vector Builder.

    Maria Pennuto

    University of Padova, Italy

  • The VectorBuilder lentivirus vectors demonstrate high transduction efficiency. The team is highly professional in vector design and production.

    Yichuan Wang

    Frederick National Lab for Cancer Research, USA

  • Nuestro laboratorio utiliza VB rutinariamente hace mas de 8 años. El servicio es impecable, fácil de diseñar plásmidos y con una calidad insuperable. Los envíos a Argentina son rápidos, sin trabas y con un excepcional servicio de atención al cliente en español .

    Alejandro Orlowski

    CIC-UNLP-CONICET, Argentina

  • The experience working with the great team at VectorBuilder, specifically with Joaquin Bozzo, has been a refreshingly smooth and enjoyable experience. Joaquin has consistently anticipated and intercepted various hurdles that our team overlooked and has proactively pushed forward one of the most urgent parts of our current pipeline. I look forward to collaborating with Joaquin and the VectorBuilder team many more times in the future.

    Sacha Schermerhorn

    Stealth, USA

  • VectorBuilder has allowed us to rapidly iterate and expand our cell editing needs. Not only do they supply a service that allows easy, quality vectors to be delivered, but they have outstanding technical and customer support. The territory manager Alejandro Izurieta has gone above and beyond to get us information we need, or connect us to the right person. We will continue to use VectorBuilder in the future for all our vector needs.

    Alan Mardinly

    Director of Biology, Science (California), USA

  • Vectorbuilder consistently provides high-quality lentivirus at an affordable price, and the delivery time is the fastest I have seen compared to the competitors. They are prompt with updates and provide useful technical advice.

    Arensman Mike

    Volastra Therapeutics, USA

  • The services provided by VectorBuilder are excellent. I had a few vector constructs made by the VectorBuilder. The description of the constructs by their software is excellent. The technical team of the company seems to have a sound knowledge and the technical suggestion regarding vector construction given to me by them were excellent.

    Saeed-ul-Hassan Khan

    Quaild-i-Azame University, Pakistan

  • VectorBuilder has been the partner every researcher would wish for during those dark moments of paper revision. They offer the complete package: a wide range of viral vector design options, an extremely user-friendly and intuitive website, direct communication, personal and knowledgeable step-by-step guidance throughout the designing and ordering process, accountability, amazing discounts, unique customer support, fast shipping, and guaranteed virus titers and efficiency. So here’s my big thumbs up for a great product and service provider who has proven indispensable in addressing my research questions!

    Evgenia Salta

    Katholieke Universiteit Leuven/VIB, Belgium

  • VectorBuilder did vector construction and lentivirus packaging for my shRNA knockdown experiment. The transduction efficiency of the lentivirus was high. Their staff were very considerate, and related technical questions were addressed quickly. I’ve finished many experiments and I’m preparing the manuscript for submission.

    Mengyuan Fan

    School of Nature Conservation, Beijing Forestry University, China

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