VectorBuilder is proud to share our client's testimonials:
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VectorBuilder has been instrumental in supporting my research by providing timely and reliable vector cloning and virus packaging services. Joaquin is always responsive to my requests and vector design needs, efficiently addressing them with care and attention to detail. His dedication to the success of my projects has contributed to several publications. I highly recommend their services.
Dr. Bogang Wu
Harvard Medical School, USA
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In our recent publication titled “Dietary ω3 Fatty Acids Inhibit Tumorigenesis in a MYCN-Driven Neuroblastoma Mouse Model” (Cancers 2024, 17, 362), we utilized the MYCN ORF expression vector custom-built by VectorBuilder, which played a vital role in driving the success of our study.
Our lab frequently orders from VectorBuilder, and their service has always been outstanding. The team is highly responsive and collaborative and consistently delivers high-quality constructs and glycerol stocks with quick turnaround. They work hand-in-hand with us throughout the design and ordering process, ensuring precision and performance.
The MYCN ORF vector was central to our project on MYCN-driven neuroblastoma, and it performed robustly in both in vitro and in vivo models. VectorBuilder’s products and support remain valuable assets in our molecular biology research.
I highly recommend VectorBuilder to other scientists looking for dependable, custom-built vector solutions.
Dr. Vishwaben Mukeshbhai Patel
University of Texas at Austin, USA
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VectorBuilder’s unparalleled service has been key to our success engineering cell-based drug delivery systems. Anil’s exceptional support ensured our complex designs were built to our specifications.
Nick Bergo
Buck Institute, USA
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We've used VectorBuilder for three different lentiviral shRNA plasmids, and each one worked exactly as expected with reliable knockdown efficiency. The process was smooth from design to delivery, and their customer support was responsive and helpful throughout. Highly recommend them for high-quality custom vectors.
Dr. Sonja Arneaud
University of Texas Southwestern Medical Center, USA
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Two years ago, when another CRO was struggling to provide the requested clones that I ordered, I reached out to Vector Builder to try to make them for me. Very difficult clones to make due to many repeats of amino acids. They got the clones done for me with no issues and very quickly. I have been using Vector Builder since then. Along with this, working with Alejandro Izurieta (California Territory Manager) has been great. He is knowledgeable, and professional promptly answers my request and is courteous. I rely on him to get the service that I need from Vector Builder done. He is just wonderful!
Irena Levin
Takeda, USA
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VectorBuilder is my favorite company! The service is reliable, efficient and excellent. The website user interface is intuitive. The number of choices for different vectors and downstream services is exhaustive, and the prices are reasonable. Furthermore, the team is receptive to feedback and queries. Compared to the old days of cloning, VectorBuilder now saves us enormous time and money, and frees us up to focus on the experimental questions rather than getting bogged down with making constructs.
Dr. Timothy Cripe
Nationwide Children’s Hospital, USA
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We are testing different vectors for T cell therapy, and VectorBuilder provides a one stop solution for design, construct and manufacturing numerus lentiviral vectors for us. One of our vector was GMP manufactured by VectorBuilder and move to FDA approved clinical trial. We had great experience working with VectorBuilder, from communication to product QC, high level of service.
Xueqing Xia
UT MD Anderson Cancer Center, USA
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I have been using Vector Builder to purchase vectors designed to express shRNA. I have found the technical support very helpful and friendly. They will make suggestions that will improve the vectors I design. Customer support is also quite fast in their responses to my questions and have also been quite accomodating with some of my requests. They also provide very helpful diagrams of their vectors that make it easy for anyone to visualize. I highly recommend Vector Builder.
Dr. Victor Ruiz-Velasco
Penn State College of Medicine
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I am very satisfied with the constructions (double mutants) made by Vectorbuilder. The service is very serious and rigorous. They started by verifying our plasmid by doing digestions. As this was not enough, they even sequenced part of the plasmid, which then ensured the success of the constructs. Constant email exchanges for verification steps were ensured with almost instantaneous responsiveness! Quite impressive! Once the sequence was clarified, production was not long, and we were able to do our experiments under excellent conditions. The results were as good as we expected. Bravo again and thank you for the efficiency, the rigor, and the seriousness.
Sabine Levi
French National Centre for Scientific Research (CNRS), France
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Our lab has been using VectorBuilder to aid in the design and synthesis of plasmids for the last 3-4 years. They have always been extremely helpful with design requests. I would highly recommend VectorBuilder's services to anyone wanting to accelerate their research progress.
Dr. Andrew Cox
Peter MacCallum Cancer Centre, Australia
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We routinely turn to VectorBuilder for the design and production of vectors used to overexpress or silence genes in our translational research on multiple myeloma. Their team has been consistently helpful in addressing technical hurdles related to gene delivery and expression in our models.
Working with VectorBuilder has always been a smooth experience — communication is clear, timelines are reliable, and the quality of the vectors has been key to the success of several experiments. They’ve become a trusted partner in our work.
Dr. Debora Soncini
University of Genoa, Italy
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We utilized two lentiviral vectors, lenti-CYP and lenti-Ctr, from VectorBuilder Inc. in our study on Lgr5+ intestinal stem cells. The lenti-CYP vector, encoding the hCYP27B1 gene, enabled de novo synthesis of locally high 1,25(OH)2D concentrations, proving crucial for our investigation. The high-quality design, including promoter specificity and integrated resistance genes, ensured reliable gene expression and successful transduction. The control vector, lenti-Ctr, further allowed precise experimental comparisons. VectorBuilder's products significantly contributed to the success of our research, and I highly recommend their custom vector services for advanced molecular biology applications.
Dr. Shaikh Nisar Ali
Long Island University, USA
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VectorBuilder's service is simply amazing. Even if you only have an idea of what you want to do, the VectorBuilder experts will help you make it happen. The service is straightforward and really accommodating. This includes fast delivery and quick responses to queries. I recommend the service to all my colleagues and will definitely use them again for future projects.
Dr. Stephan Kuenzel
TU Dresden, Germany
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We ordered adenovirus from VectorBuilder to overexpress our protein of interest in primary mouse hepatocytes. The ordering process, including vector design, was very fast and easy. We received the plasmid and adenovirus within the time frame that was stated during the ordering process and the transduction efficiency of the adenovirus was very high, enabling us to use a low MOI. As a bonus, we also received the control Ad-EGFP adenovirus for free. In the future, I will not use any more siRNA or classical transfection methods on primary mouse hepatocytes, just adenoviruses from VB! I can highly recommend VectorBuilder's services for vector design and adenovirus production.
Alexander Mayer
University of Würzburg, Germany
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Vectorbuilder is timely, communicative, easy to work with, and—most importantly—skilled at producing very high-quality viruses. We have found that the optimal multiplicity of infection for gene-editing experiments using an AAV6 donor supplied by VectorBuilder is lower than other published reports, suggesting that the provided virus is consistently of very high potency. Knowing this saves money and time.
Dr. Brock Roberts
Allen Institute for Brain Research, USA
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One year, over 10 constructs and transgenic fly lines further within a year, I want to thank VB and especially Joseph Perez for their excellent service. Dedicated to getting us the vectors we need, and advancing our follow-up applications- thank you for helping us advance our work!
Jelly Soffers
University of Missouri - Kansas City, USA
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I have been working with VectorBuilders since 2017 and generated a knock-in Long Evans rat model that recapitulates neuronal and skin disorders found in humans. In addition, we have designed and generate several plasmid constructs with them. In the past year, Ricky Nemeth, PhD, our Territory Manager, has been very supportive and fantastic to work with. In all, the entire team of VB are great to work with as they are responsive to queries and provide us good quality vectors, viral constructs and viral particles.
Martin-Paul Agbaga
University of Oklahoma Health Sciences Center, USA
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Quality, fast and easy. I must say that VectorBuilder is the best. Very good support during all the order process as well, from the design to the shipment.
Vitor Oliveira
Universidade Federal de São Paulo, Brazil
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Dr. Jen Kong and Jessi Toumeh have been absolutely wonderful to work with on my project to design a very involved viral targeting strategy. I have changed multiple aspects of the vectors and asked them so many questions. Each time they have happily altered the designs, answered my questions, or dug into the literature to find the answers. It has been such a pleasure to work with them. I am so grateful for their patience and expertise. I greatly look forward to future projects with them!
Dr. Lovisa LjungQvist Brinson
University of Pittsburgh, USA
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VectorBuilder was an amazing resource during my PhD and served me months, if not years, of time that I would otherwise have spent cloning. The support team was great, and the construct was of extremely high quality!
Dr. Maggie Fye
Vanderbilt University, USA
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I ordered the Myocardin overexpression eGFP tagged plasmid for Co-IP and it works great. But even moreso, the customer support I received from Dr. Joseph Perez was remarkable. He helped me with questions regarding my experimental design and when I needed to order more purified plasmid over the winter break, he made sure it was delivered to the lab upon my return so I could get back to experiments immediately. I would highly recommend Vector Builders just because of the amazing customer service provided by Joseph. I appreciate you so much Dr. Joseph Perez, thanks for all of your support and excellent delivery of services! Vector Builder, please give him a raise, he deserves one!!!!
Dr. Skylar King
University of Missouri School of Medicine, USA
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I had a great experience with the service and Maria solved all our doubts.
Julian Bergier
Stamm Bio, Argentina
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Reliable, precise, and fast, we were well-assisted and supported on purchases, agreements, and technical aspects. For many years we have been working with Vector Builder.
Maria Pennuto
University of Padova, Italy
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The VectorBuilder lentivirus vectors demonstrate high transduction efficiency. The team is highly professional in vector design and production.
Yichuan Wang
Frederick National Lab for Cancer Research, USA
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Nuestro laboratorio utiliza VB rutinariamente hace mas de 8 años. El servicio es impecable, fácil de diseñar plásmidos y con una calidad insuperable. Los envíos a Argentina son rápidos, sin trabas y con un excepcional servicio de atención al cliente en español .
Alejandro Orlowski
CIC-UNLP-CONICET, Argentina
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The experience working with the great team at VectorBuilder, specifically with Joaquin Bozzo, has been a refreshingly smooth and enjoyable experience. Joaquin has consistently anticipated and intercepted various hurdles that our team overlooked and has proactively pushed forward one of the most urgent parts of our current pipeline. I look forward to collaborating with Joaquin and the VectorBuilder team many more times in the future.
Sacha Schermerhorn
Stealth, USA
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VectorBuilder's online vector design tool is very efficient, quick and reliable. Special thanks to the French territory manager who is easy to communicate with and gave us very useful advice.
Laure LECOIN
Collège de France, France
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VectorBuilder makes the process of designing and building vectors easy and efficient. Justin Mirus, as the lead, and the unique and energetic design team are promptly ready to help and support our request and advise us with their great expertise and effective services.
Denise Panella
Glycostem, Netherlands
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VectorBuilder is an amazing way to save my time for the generation of my plasmid and provide excellent downstream services. You can get any custom designed vectors you want at a very good price. I am sure I will order the vectors I need in the near future.
Pengchao Zhang
Houston Methodist Research Institute, USA
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We applied
CRISPR cas9 nickase in our study. VectorBuilder helped us design the gRNAs and construct plasmids with double gRNAs and double selection markers (EGFP/puromycin). The gRNA specificity is quite good, better than available online design tools. We got the knockout cell lines in the first run of electroporation with no off-target events. I would recommend VectorBuilder to CRISPR cas9 users.Jie Qin
University Clinic Cologne, Germany
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VectorBuilder has provided incredible value and customer service throughout the entire process from product selection, custom design assistance, order submission, status reports and ultimate delivery management. The custom products I purchased from them performed exactly as advertised and in fact surpassed my expectations. I would recommend VectorBuilder to anyone requiring this type of product.
Frank Borriello
Alloplex Biotherapeutics, USA