Vectors for Human ABHD12

Gene Information

  • Offical Gene Symbol ABHD12
  • Species Human ( Homo sapiens )
  • Offical Full Name abhydrolase domain containing 12
  • Other Aliases ABHD12A; BEM46L2; C20orf22; PHARC; dJ965G21.2
  • Other Desigations monoacylglycerol lipase ABHD12; 2-arachidonoylglycerol hydrolase; abhydrolase domain-containing protein 12
  • Gene Type protein-coding
  • Summary
    This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
  • NCBI Gene ID 26090
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ABHD12(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABHD12 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human ABHD12 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human ABHD12 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human ABHD12 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human ABHD12 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABHD12 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human ABHD12 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $99
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Human ABHD12 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human ABHD12 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABHD12 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human ABHD12 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   $99
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Human ABHD12 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   $239
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