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Vectors for Human BAG3

Gene Information

  • Offical Gene Symbol BAG3
  • Species Human (Homo sapiens)
  • Offical Full Name BAG cochaperone 3
  • Other Aliases BAG-3; BIS; CAIR-1; MFM6
  • Other Desigations BAG family molecular chaperone regulator 3; BCL2 associated athanogene 3; BCL2-binding athanogene 3; Bcl-2-binding protein BIS transcript 2; bcl-2-binding protein Bis; docking protein CAIR-1
  • Gene Type protein-coding
  • Summary
    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 9531
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human BAG3(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BAG3 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human BAG3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human BAG3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human BAG3 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human BAG3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BAG3 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human BAG3 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human BAG3 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human BAG3 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BAG3 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human BAG3 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human BAG3 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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