Human IL10 (Gene ID: 3586) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol IL10
Species Human (Homo sapiens)
Offical Full Name interleukin 10
Other Aliases CSIF; GVHDS; IL-10; IL10A; TGIF
Other Desigations interleukin-10; T-cell growth inhibitory factor; cytokine synthesis inhibitory factor
Gene Type protein-coding
Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020] Annotation information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
NCBI Gene ID 3586
RefSeq Transcript
NM_000572.3; NM_001382624.1
RefSeq Protein
NP_000563.1; NP_001369553.1
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human IL10 expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human IL10 expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human IL10 expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human IL10 expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human IL10 expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human IL10 shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human IL10 shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human IL10 shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human IL10 shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human IL10 CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human IL10 CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human IL10 CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including: