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Vectors for Human LEF1

Gene Information

  • Offical Gene Symbol LEF1
  • Species Human (Homo sapiens)
  • Offical Full Name lymphoid enhancer binding factor 1
  • Other Aliases LEF-1; TCF10; TCF1ALPHA; TCF7L3
  • Other Desigations lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF1-alpha
  • Gene Type protein-coding
  • Summary
    This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • NCBI Gene ID 51176
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human LEF1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LEF1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human LEF1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human LEF1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human LEF1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human LEF1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LEF1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human LEF1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human LEF1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human LEF1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LEF1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human LEF1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human LEF1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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