VectorBuilder offers many popular vector components that users can choose from when designing their vectors. The tables below provide detailed information on these popular components, which are listed separately by category.
Note:
Linkers, which are used to connect multiple ORFs driven by a single promoter, come in two types:
  • Read-through linker (e.g. fusion linker or 2A peptide): It assumes that the upstream ORF lacks stop codon such that translation runs from the upstream ORF through the linker into the downstream ORF.
  • Non-read-through linker (e.g. IRES): It assumes that the upstream ORF ends with stop codon such that translation of the upstream ORF terminates before reaching the linker.