Drug Selection Cassettes

VectorBuilder offers many popular vector components that users can choose from when designing their vectors. The tables below provide detailed information on these popular components, which are listed separately by category.
Selection Cassettes
NameDescriptionApplication NotesSelection DrugReferencesSequence
Neo-cassettemPGK promoter driving Neo with SV40 late pAAllows cells to be resistant to geneticin (G418).Geneticin (G418)Engineered by VectorBuilder View
Puro-cassettemPGK promoter driving Puro with SV40 late pAAllows cells to be resistant to puromycin.PuromycinEngineered by VectorBuilder View
LoxP-Neo-LoxPmPGK promoter driving Neo with SV40 late pA, flanked by LoxPAllows cells to be resistant to geneticin (G418); can be deleted by Cre recombinase.Geneticin (G418)Engineered by VectorBuilder View
FRT-Neo-FRTmPGK promoter driving Neo with SV40 late pA, flanked by FRTAllows cells to be resistant to geneticin (G418); can be deleted Flp recombinase.Geneticin (G418)Engineered by VectorBuilder View
LoxP-Puro-LoxPmPGK promoter driving Puro with SV40 late pA, flanked by LoxPAllows cells to be resistant to puromycin; can be deleted by Cre recombinase.PuromycinEngineered by VectorBuilder View
FRT-Puro-FRTmPGK promoter driving Puro with SV40 late pA, flanked by FRTAllows cells to be resistant to puromycin; can be deleted by Flp recombinase.PuromycinEngineered by VectorBuilder View
3xP3-DsRedDsRed fluorescent marker driven by 3xP3 promoterUsed for identification of genetically engineered fly lines.-Insect Biochem Mol Biol. 32:1221 (2002) View
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